Top 10 companies in synthetic biology Product Industry

Synthetic biology is a broad term that carries a few definitions. Generally, it’s considered to be a field of science that involves the construction and use of biological components that do not exist in nature. The process has enormous potential in transforming medicine, food, and materials. As such, the industry is primed for remarkable growth. Valued at $9.5 billion in 2021, BCC Research estimates the market will reach $33.2 billion by 2026, at a CAGR of 28.4%.

There are several key reasons for the market’s expansion. First, many of the applications for synthetic biology have large addressable markets with a modest penetration rate. As these penetration rates accelerate, the industry will experience explosive growth. Second, exciting new technologies are driving high levels of innovation within the industry. Some examples include ultra-high-throughput screening platforms for organism design, enzymatic DNA synthesis and novel gene-editing platforms. Third, the industry is focusing on value-added products, placing less emphasis on cost-sensitive, commodity products.

With a promising future ahead, BCC Research has, in no particular order, broken down the top ten market players in synthetic biology.

The leading companies in synthetic biology

1. Agilent Technologies

Agilent is a spin-off of Hewlett-Packard, otherwise known as HP, and is a company that manufactures and markets testing and measurement products. With a core focus on providing next-generation sequencing workflow tools, Agilent enjoyed revenues of $5.3 million in 2020.

2. Amyris

Founded in 2003 at the University of California, Amyris is developing and commercializing a synthetic biology platform for the production of specialty chemicals. The company developed its Hyper-integration for rapid yeast strain engineering (Hi-Ryse) platform, which allows it to design, engineer, optimize and scale up synthetic biology-developed organisms for industrial fermentation.

3. Codexis

Codexis is a protein-engineering company involved in multiple industries, including pharmaceuticals, fine chemicals, biotherapeutics, food and beverage, and agriculture. Codexis is focused on a synthetic biology platform that can develop enzymes for specialized purposes. Code Evolver, the company’s platform, creates libraries of gene variants encoding biocatalysts with novel functions.

4. Eurofins Scientific

Founded in 1987, Eurofins Scientific is engaged in offering analytical services to carry out testing to improve health and safety. Eurofins is the CRO that deals in food, pharmaceutical, cosmetic product testing, environment and agroscience through its subsidiaries. The company independently deals in discovery pharmacology, forensics, advanced material sciences, in testing and laboratory services for genomics, as well as for supporting clinical studies. It is also emerging in specialty esoteric and molecular clinical diagnostic testing in Europe and the U.S.

5. GenScript

GenScript was founded in 2002 and is a company that manufactures and markets genomic and proteomic tools for the life science industry. The main business areas include life science services and products, biologics development services, industrial synthetic biology products and cell therapy.

6. Ginkgo Bioworks

Ginkgo is a spinout from the Massachusetts Institute of Technology. The company designs and operates production systems using designed organisms, and is developing organisms that can produce a range of products. These include flavors and fragrances, industrial enzymes, nutritional ingredients, cosmetics, sweeteners and pharmaceuticals.

7. Merck KGaA

Merck KGaA, a 344-year-old company, is a major pharmaceutical and chemical manufacturer with sales and marketing in more than 60 countries. The company is particularly strong in the oncology and neurology markets.

In July 2015, Sigma Aldrich formed an alliance with Genapsys to co-market the electronic sequencer, Genius. Sigma Aldrich viewed this partnership as contributing to its research and applied markets businesses. The Genius sequencer is a small instrument and uses a chip-based electronic detection system.

8. Novozymes A/S

Novozymes A/S is the largest global producer of industrial enzymes, with an estimated global market share of 47%. Novozymes participates in all areas of the industrial enzyme business, including household detergents, food and beverage, bioenergy, agriculture and pharmaceuticals.

9. Thermo Fisher Scientific

Formed in 2006 from a merger of Thermo Electron Corp. and Fisher Scientific, Thermo Fisher Scientific produces and markets instruments, reagents, software and services for the life science industry.

The company has four business segments: Life Science Solutions (24.4% of second quarter 2018 revenues), Analytical Instruments (20.5%), Specialty Diagnostics (14.2%) and Laboratory Products and Services (40.9%).

10. Twist Bioscience

Founded in 2013, Twist Bioscience develops and commercializes next-generation platforms for DNA synthesis. The company is using microarray-based methods to synthesize DNA. Oligonucleotides are synthesized within holes inside of the nano-wells on Twist’s wafer. Oligonucleotides can be combined to build a gene by depositing one oligonucleotide into each of the nano-well holes.

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