The Advantages and Disadvantages of Insulin Drug and Delivery Technologies

insulin-delivery

With the advancement of technology within the drug delivery systems industry, insulin delivery systems have rapidly evolved to suit the user in terms of convenience and ease of use. BCC analysts predict that the market growth is attributed to factors such as the increasing incidence of diabetes and novel insulin drug and delivery technologies.

Insulin drug and delivery technology

Insulin delivery systems are categorized into four sections by BCC Research: syringes, insulin pens, insulin pumps, and smart pens. Insulin delivery systems are vital in the daily management and care of patients with diabetes. In our latest report on insulin drug and delivery technologies, our analysts determine that traditional syringes and insulin pumps are being replaced by reusable and disposable insulin pens due to the latter’s portability, greater dosage accuracy, and ease of use.

With the healthcare industry and its care providers already working overtime to provide the best quality of care for patients, the introduction of technology that allows patients to gain autonomy over the management of their disease is a welcome introduction by all. As with most chronic diseases, patients don’t always fall under a one size fits all approach in terms of their treatment. Through research and developments in insulin technology, patients can administer insulin as and when the time is suitable or necessary for themselves in line with their individual health plan.

Conventional technologies as well as advanced technologies exist within the market. Each technology is suited to the different needs and economic situations of the patient.

The use of syringes in insulin drug and delivery technology

The administration of multiple daily injections of long-acting basal insulin and rapid-acting prandial insulin formulations is the most recommended intensive insulin therapy regimen for type one diabetics. The global market for drug and delivery devices by type reveals that syringes will reach $36,957.2 million by 2027 at a CAGR of 8.7% situating itself way ahead of the other devices. Syringes serve as the standard for intensive type one diabetes management; however, this is not to say it is without its grievances.

The number of insulin injections required exceeds three per day, which is timely and inconvenient for patients. Research suggests it may negatively impact good glycemic control. The main advantages and disadvantages of syringes as an insulin delivery technology are:

Advantages

  • Cost-effective
  • Easy to use and operate
  • Maintenance-free devices
  • Available in different unit strengths as per the individuals' needs

Disadvantages

  • Accuracy depends on the person using it in terms of mixing the doses, filling volumes, and checking the graduation marks
  • There is a social stigma surrounding syringes and their use of them in public for illegal substances
  • Smaller parts make it difficult to manage during work, school, and travel routines

Insulin pens Vs syringes in insulin delivery

An insulin pen differs from a syringe in that it is an injection device that is around the shape and size of a large marker pen. It helps to deliver insulin into the fatty tissue via a short, thin disposable needle. Frequently used by travelers, insulin pens integrate the medication and delivery system, making them more convenient than syringes. The user simply twists or snaps on a new needle, dials a dose, injects the insulin, and discards the used needle into a needle-safe container.

Advantages

  • Can be either disposable or reusable
  • Smaller and lighter in weight
  • The pen is already pre-filled or uses a pre-filled, self-contained cartridge.
  • Insulin pens have shorter, thinner needles which tend to be less painful when inserted

Disadvantages

  • More expensive than insulin provided in a vial
  • Insulin needles are an added cost
  • Requirement of different kinds of insulin with injections may require more than one pen
  • Not all insulin types are available for use in insulin pen devices

The first automatic insulin delivery device

Invented in the 1980s, insulin pumps are a step away from traditional manual devices. The insulin pump is a complex battery-operated, computerized electronic device that can be programmed to provide continuous subcutaneous insulin infusion. The insulin pump is programmed and can be customized to meet individual needs. It delivers rapid-acting insulin to the patient continuously to ensure basal blood insulin levels. Immediately before eating, the patient manually programs the pump to deliver a larger supplemental dose (bolus dose) of rapid-acting insulin. Although convenient, insulin pumps come with inherent limitations, including the increased likelihood of diabetic ketoacidosis, irritation, and scarring of the insertion site. The future of insulin pump therapy is promising, as it is an excellent alternative to conventional injections for type one diabetes patients of all ages.

Advantages

  • They offer more precise amounts of insulin, which supports tighter control over blood sugar levels
  • More convenient and discreet than an injection
  • Provides more flexibility in the user’s daily life

Disadvantages

  • Insulin pumps need to be worn most of the time, impacting the user’s participation in physical activities like sports
  • Cartridges and infusion sets are more expensive than syringes
  • The pumps are breakable

What does the future of insulin delivery technology look like?

Smart pens show great promise for diabetes management. Smartpen technology records the amount and timing of each insulin dose and wirelessly transmits the information to a dedicated mobile application. It also offers dosing recommendations and prepares reports for healthcare professionals. Within the global market for insulin delivery technology smart pens deliver the highest compound annual growth rate over the forecast period at 12.6%, expected to reach $7,666.6 million by 2027 from $3,554.1 million in 2022.

Smart insulin pens are relatively new to the insulin delivery device game so clear advantages and disadvantages aren’t as researched as others. However, the gap in the market for an insulin device which reflects the current relationship between healthcare and technology is being cornered by the introduction of these devices. These evolved insulin pens gained digital displays and memory of the most recent doses. Smart pens are designed to be simple to use. Once you’ve downloaded the app to your smartphone and paired it with your pen, you’re ready to go. The device sends real-time data to the app via Bluetooth connection, defining smart pens as the future of insulin delivery device technologies.

Global markets for insulin drug and delivery technologies

The tides are changing within the insulin delivery industry, and smarter technologies are slowly gaining momentum through the market chain. In a society in which wearable technology can monitor your heart and track health conditions, patients have an increased awareness of self-care which reflects the growing popularity of smart insulin drug delivery technology that provides basic health data in a user-friendly format.

The global market for insulin drug and delivery technologies is expected to grow at a compound annual growth rate (CAGR) of 9.8% to reach over $88.9 billion by the end of 2027. BCC analysts predict a strong future for insulin drug delivery systems in the adoption and development of smart devices, as discussed in our latest report: Global Markets for Insulin Drug and Delivery Technologies.

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Written by Katie Biddle on Oct 20, 2022 10:35:00 AM

Topics: Life Sciences, Health Maintenance

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