Insights from BCC Research

3D Cell Culture: Global Markets and Out-of-this-World Applications

Posted by Laurie L. Sullivan on Jul 19, 2017 10:00:00 AM

Fast-moving developments in 3D cell culture tools and technologies are accelerating cancer research and its clinical applications, as well as other areas of medical research and safety applications. BCC Research forecasts some segments of the global 3D cell culture market to have five-year compound annual growth rates as high as 44% through 2021 (e.g., 3D applications in toxicology for pharmaceutical development). In another example, neurological safety testing could grow from being a $5 million segment in 2015 to $95 million by 2021, according to BCC Research’s study, 3D Cell Cultures: Technologies and Global Markets.

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Topics: Life Sciences, Biotechnology

Engineered Proteins Rise to Meet Challenges of Diseases and Infections

Posted by Laurie L. Sullivan on Jun 29, 2017 10:00:00 AM

Continuous research and innovations in drug discovery are driving modest growth in the global market for bioengineered protein therapeutics. According to an analysis by BCC Research, other growth factors include more sedentary lifestyles, the rising incidence of chronic illnesses, and an increasing awareness of enzymatic and other disorders. Bioengineered proteins are widely used as therapeutics because of their high potency and reduced side effects. They are created by genetically modifying living cells using recombinant DNA technology. The model organisms for these include Escherichia coli bacteria, yeast, and mammalian cell cultures. Protein drugs can help treat chronic diseases such as asthma, rheumatoid arthritis, cancer, and diabetes.

The global market for bioengineered protein drugs is expected to reach $228.4 billion by 2021 from $172.5 billion in 2016, growing at a five-year compound annual growth rate (CAGR) of 5.8%. The United States, which is the largest market, should attain $148.7 billion in 2021, demonstrating a five-year CAGR of 9.7%. The European market could reach $39.5 billion at a CAGR of 0.3% from 2016 through 2021. The emerging markets are predicted to total $40.2 billion in 2021, up from $39.8 billion in 2016, representing a five-year CAGR of 0.2%.


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A rise in revenues from monoclonal antibodies, peptide hormones, blood products, and therapeutic enzymes has boosted the US market. In Europe, competition from the entry of biosimilars and Brexit (the exiting of Britain from the European Union in 2016) have had adverse effects on the market. The emerging markets have shrunk slightly due to lack of awareness and facilities to market bioengineered products in countries such as India and Brazil. These regions are unfamiliar with protein therapeutics and prefer chemical drugs. Also, many of these products are marketed in a limited number of countries; thus people do not have convenient access to the drugs nor to information about them.

The therapeutic use of monoclonal antibodies is expected to increase during BCC Research’s forecast period. Other protein therapies, including some vaccines and therapeutic enzymes, are in demand as the result of the increasing incidence of hormonal disorders, diabetes, and infertility. Increased research and development spending, growing competition, patent expiries, and changing lifestyles are factors shaping the protein therapeutics market. “Global market growth has been favorably affected by the rapid increase in new medical technologies, heightened awareness, the rise in patent approvals, improved diagnosis of diseases, and expansion of healthcare in emerging markets,” says BCC Research analyst Shalini S. Dewan.


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Topics: Life Sciences, Biotechnology

Gut Instinct: The Human Microbiome Predicts Response to Therapy

Posted by Laurie L. Sullivan on Jun 15, 2017 11:15:00 AM
The human microbiome is a significant commercial opportunity for the life sciences sector. Scientific studies have clearly shown the role of the microbiome in the pathogenesis of many mainstream diseases. Microbiome-based drugs and diagnostics are being studied in a wide range of disorders, including cancers, gastrointestinal or gut conditions, Crohn’s disease and colitis, dental problems, and chronic infections. Exploiting the human microbiome could help fill gaps in the conventional treatment options for disease. Rare or orphan diseases that are not currently addressed by pharmaceutical companies are another area of emphasis worldwide.

Market Highlights from BCC Research
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Topics: Life Sciences, Biotechnology

Synthetic Biology Aids Terrestrial and Extraterrestrial Agriculture

Posted by Laurie L. Sullivan on May 10, 2017 10:55:08 AM

Synthetic biology, which combines the principles of computer science, engineering, and biology, has become established as an important discipline in the life sciences industry. As put by USC’s Leonardo Morsut: “Synthetic biology is…trying to bring the engineering approach of building things into biology.” In addition to its enormous potential for future applications, synthetic biology has significant near-term commercial opportunities. The list of new products and applications is growing. Applications include specialty chemicals, enzymes, synthetic genes and cells, as well as pharmaceuticals, agricultural seeds, vaccines, biofuels, and chassis microorganisms.

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Topics: Biotechnology, life